Multi-scale modeling of geometric flow control in lateral flow assays

This work employs multi-scale modeling, integrating micro and macro-scale investigations, to enhance understanding of lateral flow assays (LFAs). It analyzes porous membrane properties, explores geometric influences on fluid flow via single and two-phase models, and quantifies signal intensity using a convection-diffusion-reaction model. This approach optimizes LFA design for improved sensitivity and specific applications, including multiplexed LFAs.